Fig. 2 | Scientific Reports

Fig. 2

From: Bioinformatics approaches to multi-omics analysis of the potential of CDKN2A as a biomarker and therapeutic target for uterine corpus endometrial carcinoma

Fig. 2

CDKN2A is upregulated in UCEC patients and associated with poor prognosis. (A) CDKN2A expression in pan-cancer. Blue represents normal, red shows tumor. (B) CDKN2A expression between normal and primary tumor tissue. (C) CDKN2A expression in different cancer stages. (D) CDKN2A expression in different histological subtypes. (E) Overall survival rate of low and high CDKN2A expression groups. 174 tumor samples from GTEx were analyzed. Log-rank p = 0.0055. Group cutoff: median. Hazard ratio (HR) = 2.9, p = 0.0078. HR was calculated based on Cox PH model. 95% confidence interval is shown as dotted line. *: p < 0.05; **: p < 0.01; ***: p < 0.001.

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