Table 2 Outcomes of open surgery, non-operative management and angiography.

From: Comparison of management options for spontaneous bleeding into soft tissues in patients with COVID-19

Parameters

NOM (n = 51)

OS (n = 18)

AG/AG + TAE (n = 60)

p-value

Sex (M/F), n (%)

7 (14)/44 (86)

0 (0)/18 (100)

9 (15)/51 (85)

0.223

Age (y), M (SD)

73.1 (12.7)

71.6 (8.3)

73.2 (10.9)

0.856

BMI, M (SD)

30 (6.7)

31 (8.6)

30 (6.0)

0.619

Plasma transfusion, n (%)

14 (27)

14 (78)

27 (45)

 < 0.001

NOM vs. OS 0.002 NOM vs. AG 0.087 OS vs. AG0.059

RBC transfusion, n (%)

38 (75)

17 (94)

48 (80)

0.193

Hemoglobin on admission (g/l), M (SD)

121.5 (0.6)

125.9 (42.2)

133.4 (19.4)

0.171

Hematocrit on admission, M (SD)

36 (12.1)

38 (12.4)

39 (7.7)

0.198

Min hemoglobin level (g/l), M (SD)

72.3 (15.7)

57.4 (15.4)

66.2 (17.3)

0.004

NOM vs. OS 0.004 NOM vs. AG 0.099 OS vs. AG0.099

Min hematocrit level, M (SD)

22 (4.7)

18 (4.5)

21 (6.4)

0.021

NOM vs. OS 0.017 NOM vs. AG 0.197 OS vs. AG 0.108

Max hematoma volume (ml), Me [Q1, Q3]

667 [400;1097]

1200 [852.5;1500]

913.5 [596.5;1565]

0.187

Treatment in ICU, n (%)

41 (80)

18 (100)

51 (85)

0.130

Vasopressor support before onset of bleeding, n (%)

16 (31)

16 (89)

23 (38)

 < 0.001

NOM vs. OS > 0.001 NOM vs. AG 0.571 OO vs. PЭ < 0.001

Artificial ventilation before onset of bleeding, n (%)

6 (12)

6 (33)

8 (13)

0.077

Pron position before onset of bleeding, n (%)

23 (45)

7 (39)

27 (45)

0.888

NEWS2 (points), M (SD)

5.5 (2.8)

5.4 (3.1)

5.3 (2.7)

0.939

SOFA (points), Me [Q1, Q3]

3 [2;5]

6 [3;8]

3 [2;7]

0.451

APACHE II (points), Me [Q1, Q3]

15 [6;20]

16 [8;25]

18 [11;25]

0.136

30-day mortality, n (%)

27 (53)

13 (72)

26 (43)

0.094

  1. BMI, body mass index; ICU, intensive care unit; NEWS2, National Early Warning Score 2; SOFA, sequential organ failure assessment; APACHE II, acute physiology and chronic health evaluation II.