Table 4 Comparison of therapeutic embolization, preventive embolization and diagnostic angiography groups.
Parameters | Therapeutic embolization (n = 27) | Preventive embolization (n = 14) | Diagnostic angiography (n = 19) | P-value | |
---|---|---|---|---|---|
Age (y), M (SD) | 75.7 (12.9) | 69.8 (8.1) | 73.3 (9.5) | 0.158 | |
Sex (F/M) | 22/5 | 13/1 | 16/3 | 0.810 | |
Time from onset of COVID-19 to bleeding (days), M (SD) | 13.7 (5.3) | 14.1 (3.3) | 15.5 (4.9) | 0.524 | |
Time from the start of anticoagulant therapy to hematoma detection (days), M (SD) | 8.7 (5.7) | 8.3 (3.3) | 11.6 (5.2) | 0.146 | |
Anticoagulant therapy, n (%) | Unfractionated heparin | 1 (3.7) | 0 | 0 | 0.956 |
Low molecular weight heparin | 23 (85.2) | 12 (85.7) | 17 (89.5) | 0.282 | |
Novel Oral Anticoagulants (NOAC) | 1 (3.7) | 0 | 0 | 0.916 | |
Combination | 2 (7.4) | 2 (14.3) | 2 (10.5) | 0.781 | |
ASA, M (SD) | 3.8 (0.7) | 3.7 (0.6) | 3.7 (0.8) | 0.926 | |
NEWS 2, M (SD) | 5.1 (3.5) | 4.6 (1.7) | 6.0 (3.4) | 0.561 | |
APACHE-2 (n is number of patients in ICU), M (SD) | n = 21 18.7 (8.1) | n = 7 22.7 (10.1) | n = 13 19 (6.5) | 0.824 | |
Vasopressor support before procedure (n = 22), n (%) | 12 (44.4) | 3 (21.4) | 7 (36.8) | 0.349 | |
COVID-19 severity, n (%) | Moderate | 8 (29.6) | 8 (57.1) | 3 (15.8) | 0.023 |
Severe | 16 (59.3) | 4 (28.6) | 12 (63.2) | 0.124 | |
Extremely severe | 3 (11.1) | 2 (14.3) | 4 (21) | 0.662 | |
Hematoma location, (n) | Anterior abdominal wall | 19 | 14 | 8 | 0.002 |
Retroperitoneal space | 6 | 0 | 3 | 0.167 | |
Thoracic wall | 2 | 0 | 8 | 0.001 | |
Hematoma volume (ml), M (SD) | 1022.2 (644.9) | 1224.1 (790.5) | 887 (483.2) | 0.550 | |
Hemoglobin (g/l) before angiography, M (SD) | 76.4 (19.6) | 94.2 (28.6) | 82.3 (26.1) | 0.163 | |
Time from hematoma detection before AG (min), M (SD) | 220.4 (328.4) | 371.9 (249.8) | 348.1 (409.6) | 0.056 | |
Duration of procedure (min), M (SD) | 66.5 (43.1) | 57.4 (20.8) | 40.5 (28.2) | 0.018 | |
Subsequent open surgery, n (%) | 1 (3.7) | 2 (14.3) | 2 (10.5) | 0.466 | |
Artery dissection, n (%) | 2 (7.4) | 0 | 0 | 0.282 | |
Mortality, n (%) | 11 (40.8) | 4 (28.6) | 11 (57.9) | 0.228 |