Fig. 11

Predictive Potential of Immunotherapy in Patients with High and Low PTGES3 Expression Levels. (A-C) Correlation analyses between the dysregulation score, exclusion score, microsatellite instability (MSI) score, and PTGES3 expression. (D) Survival analysis comparing patients with high and low PTGES3 expression within the GSE91061 dataset. (E) Distribution of patients with high and low PTGES3 expression across different immunotherapy response categories. (F) Application of the subclass mapping algorithm to forecast the immunotherapy response in patients with varying PTGES3 expression levels. (G-I) Associations between the stromal score, immune score, and estimated score, and their correlation with PTGES3 expression. *p < 0.05; **p < 0.01; ***p < 0.001; NS indicates the results are not statistically significant.