Table 1 Summary of the IC50 values in the clinical isolates and laboratory strains of P. falciparum parasites. The 95% confidence intervals (95%CI) are shown in the brackets.

From: Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates

Laboratory strain

IC50 (µM) (95%CI)

Clinical Isolate

IC50 (µM) (95%CI)

Clinical Isolate

IC50 (µM) (95%CI)

W2mef

3.829

A006

1.058

A059

10.54

(3.266–4.488)

(0.194–1.511)

(7.915–15.130)

7G8

4.893

A156

2.034

173

11.06

(3.847–6.224)

(1.175–2.647)

(9.930–12.330)

Dd2

5.049

A031

3.819

14414

11.45

(4.291–5.883)

(2.790–5.411)

(18.410–21.840)

3D7

5.801

A005

3.985

A376

12.64

(5.163–6.367)

(1.100–5.841)

(11.000–14.890)

GB4

6.919

A010

6.883

A377

13.07

(5.630–9.591)

(5.299–8.037)

(8.949–25.180)

NF54

10.19

A011

4.056

A378

15.55

(8.371–12.460)

(3.214–5.125)

(11.660–21.300)

  

14400

6.655

K239

20.07

  

(5.877–7.562)

(17.170–24.990)

  

A058

8.399

A362

22.2

  

(6.201–13.260)

(18.040–30.330)

  

179

9.704

A354

22.99

  

(8.974–10.470)

(16.470–43.200)

  

A375

9.939

A007

24.19

  

(8.239–11.770)

(19.630–55.260)

    

A018

24.79

    

(18.040–45.870)