Fig. 4 | Scientific Reports

Fig. 4

From: Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway

Fig. 4

Effects of Hirudo extract on cytoskeletal F-actin polymerization in TGF-β2-induced ARPE-19 cells. F-actin expression (red immunofluorescence) was detected via immunofluorescence staining (original magnification: ×400). DAPI was used to stain the cell nucleus (blue). ***P < 0.001 vs. the control group; ###P < 0.001 vs. the TGF-β2 group; @@P < 0.01 vs. the TGF-β2 + 400 µg/mL Hirudo extract group; $P < 0.05 vs. the TGF-β2 + 800 µg/mL Hirudo extract group.

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