Fig. 1 | Scientific Reports

Fig. 1

From: FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers

Fig. 1

Genetic alteration frequency and mRNA levels of FLT3 in pan cancer and its association with prognosis. (A) FLT3 alterations (including mutations, deletions, and amplifications) were observed in pan cancer using the cBioPortal database. (B) The role of an FLT3 alteration in OS was evaluated using the cBioPortal database. The FLT3 alteration group exhibited a shorter OS than the FLT3 unaltered group in pan-cancers. (C) FLT3 expressions were observed in pan cancer using the cBioPortal database and the FLT3 mRNA level was significantly higher in AML than in any other solid cancer. (D) The role of the FLT3 mRNA level in OS and RFS were evaluated using the GEPIA2 database. A high level of FLT3 mRNA was significantly correlated with a poor prognosis only in AML.

Back to article page