Table 4 Bivariate and multivariate analysis of factors associated with drug-related problems among thyroid disease patients at ambulatory clinics in selected hospitals of Northwest, Ethiopia, from July 01-Sept 30, 2022, (n = 351).

From: Drug related problems and associated factors among thyroid disorder patients in Northwest Ethiopia

Variables

Category

DRP = 211

COR (95% CI)

AOR (95% CI)

P-value

No = 140

N (%)

Yes = 211

N (%)

Age

18–40

74 (52.9)

64 (30.3)

1

1

 
 

41–60

58 (41.4)

97 (46)

1.93 (1.2–3.08)

1.13 (0.61–2.09)

0.691

≥ 61

8 (5.7)

50 (23.7)

7.23 (3.19–16.37)

2.85 (1.05–7.69)

0.039

Residence

Rural

85 (60.7)

156 (73.9)

1.84 (1.16–2.90)

0.89 (0.41–1.94)

0.778

Urban

55 (39.3)

55 (26.1)

1

1

 

Education

Cannot read and write

60 (42.9)

136 (64.5)

2.27 (0.70–7.32)

1.34 (0.23–7.67)

0.741

Can read and write

25 (17.8)

38 (18)

1.52 (0.44–5.25)

1.39 (0.24–7.94)

0.709

Primary school

20 (14.3)

16 (7.6)

0.8 (0.22–2.96)

0.98 (0.18–5.43)

0.979

Secondary school

18 (12.9)

11 (5.2)

0.61 (0.16–2.38)

0.85 (0.17–4.34)

0.845

Diploma

11 (7.9)

4 (1.9)

0.36 (0.07–1.82)

0.700 (0.12–4.15)

0.700

Degree and above

6 (4.2)

6 (2.8)

1

1

 

Occupation

Housewife

85 (60.7)

164 (77.7)

3.22 (1.35–7.65)

1.05 (0.25–4.36)

0.945

Farmer

11 (7.8)

19 (9)

2.88 (0.95–8.74)

0.79 (0.15–4.25)

0.781

Merchant

8 (5.7)

7 (3.3)

1.46 (0.39–5.39)

0.64 (0.13–3.19)

0.585

Self-employed

9 (6.4)

7 (3.3)

1.3 (0.36–4.69)

0.93 (0.19–4.65)

0.930

Student

12 (4.3)

5 (2.4)

0.69 (0.18–2.63)

0.47 (0.08–2.90)

0.419

Government employed

15 (10.7)

9 (4.3)

1

1

 

Monthly income

< 1000 ETB

37 (26.4)

107 (51)

6.75 (1.66–27.45)

3.42 (0.74–15.84)

0.116

1000–5000

68 (48.6)

70 (33.2)

2.4 (0.59–9.67)

1.2 (0.26–5.44)

0.830

5000–10,000

22 (15.7)

20 (9.5)

2.12 (0.48–9.34)

1.89 (0.37–10.37)

0.462

No regular income

6 (4.3)

11 (5.2)

4.28 (0.79–22.93)

3.24 (0.52–20.04)

0.206

> 10,000 ETB

7 (5)

3 (1.4)

1

1

 

Marital status

Single

24 (17.1)

12 (5.7)

0.30 (0.15–0.64)

0.79 (0.19–3.12)

0.732

Divorced

10 (7.1)

17 (8.1)

1.04 (0.46–2.35)

0.83 (0.31–2.22)

0.704

Widowed

6 (4.3)

18 (8.5)

1.83 (0.70–4.76)

1.00 (0.32–3.13)

0.998

Married

100 (71.4)

164 (77.7)

1

1

 

Living condition

Living alone

13 (9.3)

10 (4.7)

0.49 (0.21–1.15)

1.09 (0.32–3.76)

0.886

Living with family

127 (90.7)

199 (43)

1

1

 

Polypharmacy

Yes

8 (5.7)

64 (30.3)

6.19 (2.97–12.95)

2.57 (1.01–6.29)

0.046*

No

132 (94.3)

147 (67.7)

1

1

 

Comorbidities

Yes

25 (17.9)

92 (43.6)

3.56 (2.1–5.93)

2.09 (1.07–4.05)

0.030*

No

115 (82.1)

119 (0.6)

1

1

 

Distance from health facility

6 h

61 (43.6)

92 (43.6)

1.68 (0.99–2.83)

1.60 (0.74–3.46)

0.233

12 h

24 (17.1)

51 (24.2)

2.37 (1.26–4.46)

1.77 (0.73–4.32)

0.206

18 h

5 (3.6)

19 (9)

4.23 (1.46–12.29)

2.68 (0.73–9.83)

0.136

24 h

1 (0.7)

5 (2.4)

5.67 (0.63–49.52)

3.61 (0.27–49.21)

0.335

1 h

49 (35)

44 (20.9)

1

1

 

Source of medication

Private

10 (7.1)

30 (14.2)

2.14 (1.01–4.54)

2.62 (1.06–6.49)

0.038*

Both Private & Government

5 (3.6)

6 (2.8)

0.86 (0.26–2.87)

1.15 (0.23–5.76)

0.864

Government

125 (89.3)

175 (82.9)

1

1

 
  1. *Indicates P < 0.05. COR: crude odds ratio; AOR: adjusted odds ratio; CI: Confidence interval.