Table 4 Bivariate and multivariate analysis of factors associated with drug-related problems among thyroid disease patients at ambulatory clinics in selected hospitals of Northwest, Ethiopia, from July 01-Sept 30, 2022, (n = 351).
From: Drug related problems and associated factors among thyroid disorder patients in Northwest Ethiopia
Variables | Category | DRP = 211 | COR (95% CI) | AOR (95% CI) | P-value | |
---|---|---|---|---|---|---|
No = 140 N (%) | Yes = 211 N (%) | |||||
Age | 18–40 | 74 (52.9) | 64 (30.3) | 1 | 1 | |
41–60 | 58 (41.4) | 97 (46) | 1.93 (1.2–3.08) | 1.13 (0.61–2.09) | 0.691 | |
≥ 61 | 8 (5.7) | 50 (23.7) | 7.23 (3.19–16.37) | 2.85 (1.05–7.69) | 0.039 | |
Residence | Rural | 85 (60.7) | 156 (73.9) | 1.84 (1.16–2.90) | 0.89 (0.41–1.94) | 0.778 |
Urban | 55 (39.3) | 55 (26.1) | 1 | 1 | ||
Education | Cannot read and write | 60 (42.9) | 136 (64.5) | 2.27 (0.70–7.32) | 1.34 (0.23–7.67) | 0.741 |
Can read and write | 25 (17.8) | 38 (18) | 1.52 (0.44–5.25) | 1.39 (0.24–7.94) | 0.709 | |
Primary school | 20 (14.3) | 16 (7.6) | 0.8 (0.22–2.96) | 0.98 (0.18–5.43) | 0.979 | |
Secondary school | 18 (12.9) | 11 (5.2) | 0.61 (0.16–2.38) | 0.85 (0.17–4.34) | 0.845 | |
Diploma | 11 (7.9) | 4 (1.9) | 0.36 (0.07–1.82) | 0.700 (0.12–4.15) | 0.700 | |
Degree and above | 6 (4.2) | 6 (2.8) | 1 | 1 | ||
Occupation | Housewife | 85 (60.7) | 164 (77.7) | 3.22 (1.35–7.65) | 1.05 (0.25–4.36) | 0.945 |
Farmer | 11 (7.8) | 19 (9) | 2.88 (0.95–8.74) | 0.79 (0.15–4.25) | 0.781 | |
Merchant | 8 (5.7) | 7 (3.3) | 1.46 (0.39–5.39) | 0.64 (0.13–3.19) | 0.585 | |
Self-employed | 9 (6.4) | 7 (3.3) | 1.3 (0.36–4.69) | 0.93 (0.19–4.65) | 0.930 | |
Student | 12 (4.3) | 5 (2.4) | 0.69 (0.18–2.63) | 0.47 (0.08–2.90) | 0.419 | |
Government employed | 15 (10.7) | 9 (4.3) | 1 | 1 | ||
Monthly income | < 1000 ETB | 37 (26.4) | 107 (51) | 6.75 (1.66–27.45) | 3.42 (0.74–15.84) | 0.116 |
1000–5000 | 68 (48.6) | 70 (33.2) | 2.4 (0.59–9.67) | 1.2 (0.26–5.44) | 0.830 | |
5000–10,000 | 22 (15.7) | 20 (9.5) | 2.12 (0.48–9.34) | 1.89 (0.37–10.37) | 0.462 | |
No regular income | 6 (4.3) | 11 (5.2) | 4.28 (0.79–22.93) | 3.24 (0.52–20.04) | 0.206 | |
> 10,000 ETB | 7 (5) | 3 (1.4) | 1 | 1 | ||
Marital status | Single | 24 (17.1) | 12 (5.7) | 0.30 (0.15–0.64) | 0.79 (0.19–3.12) | 0.732 |
Divorced | 10 (7.1) | 17 (8.1) | 1.04 (0.46–2.35) | 0.83 (0.31–2.22) | 0.704 | |
Widowed | 6 (4.3) | 18 (8.5) | 1.83 (0.70–4.76) | 1.00 (0.32–3.13) | 0.998 | |
Married | 100 (71.4) | 164 (77.7) | 1 | 1 | ||
Living condition | Living alone | 13 (9.3) | 10 (4.7) | 0.49 (0.21–1.15) | 1.09 (0.32–3.76) | 0.886 |
Living with family | 127 (90.7) | 199 (43) | 1 | 1 | ||
Polypharmacy | Yes | 8 (5.7) | 64 (30.3) | 6.19 (2.97–12.95) | 2.57 (1.01–6.29) | 0.046* |
No | 132 (94.3) | 147 (67.7) | 1 | 1 | ||
Comorbidities | Yes | 25 (17.9) | 92 (43.6) | 3.56 (2.1–5.93) | 2.09 (1.07–4.05) | 0.030* |
No | 115 (82.1) | 119 (0.6) | 1 | 1 | ||
Distance from health facility | 6 h | 61 (43.6) | 92 (43.6) | 1.68 (0.99–2.83) | 1.60 (0.74–3.46) | 0.233 |
12 h | 24 (17.1) | 51 (24.2) | 2.37 (1.26–4.46) | 1.77 (0.73–4.32) | 0.206 | |
18 h | 5 (3.6) | 19 (9) | 4.23 (1.46–12.29) | 2.68 (0.73–9.83) | 0.136 | |
24 h | 1 (0.7) | 5 (2.4) | 5.67 (0.63–49.52) | 3.61 (0.27–49.21) | 0.335 | |
1 h | 49 (35) | 44 (20.9) | 1 | 1 | ||
Source of medication | Private | 10 (7.1) | 30 (14.2) | 2.14 (1.01–4.54) | 2.62 (1.06–6.49) | 0.038* |
Both Private & Government | 5 (3.6) | 6 (2.8) | 0.86 (0.26–2.87) | 1.15 (0.23–5.76) | 0.864 | |
Government | 125 (89.3) | 175 (82.9) | 1 | 1 |