Table 2 The results of univariate and multivariate analysis affecting OS.

From: Factors affecting prognosis in patients with locally advanced and advanced esophageal cancer receiving definitive radiotherapy in plateau regions

Variables

Univariate analysis

Multivariate analysis

HR

95.0%CI

p-value

HR

95.0%CI

p-value

Age(years)

0.744

0.546–1.013

0.060

   

< 60

≥ 60

BMI

0.936

0.887–0.989

0.018

0.821

0.652–1.036

0.078

ECOG performance status

1.300

0.937–1.804

0.116

   

ECOG 0

ECOG 1

ECOG 2

The length of the lesion(cm)

1.019

0.957–1.086

0.548

   

Tumor location

0.826

0.690–0.988

0.036

0.821

0.652–1.036

0.096

Cervical

Upper-thoracic

Mid-thoracic

Lower-thoracic

Adjuvant therapy

2.028

1.480–2.779

< 0.001

1.871

1.222–2.866

0.004

Yes

No

Clinical stages

0.980

0.801–1.199

0.844

   

III

IVA

IVB

M

0.933

0.635–1.385

0.746

   

0

1

N position

 

Mediastinal

1.151

0.794–1.668

0.459

   

Supraclavicular

0.810

0.591–1.110

0.191

   

Celiac

0.989

0.724–1.352

0.946

   

Concurrent chemotherapy

0.910

0.667–1.242

0.553

   

Yes

No

Immunotherapy

1.567

1.107–2.217

0.011

1.010

0.643–1.586

0.965

Yes

No

Radiotherapy dose

1.074

0.777–1.483

0.666

   

High dose (> 54 Gy)

Standard dose (≤ 54 Gy)

PTV (cm3)

1.001

1.000-1.001

0.141

   

CTV (cm3)

1.001

1.000-1.002

0.105

   

GTV (cm3)

1.004

1.001–1.008

0.026

1.005

1.001–1.010

0.015

GTVnd (cm3)

1.006

0.998–1.013

0.148

   

New (cm3)

1.001

1.000-1.002

0.204

   
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