Table 3 The results of univariate and multivariate analyses affecting PFS.

From: Factors affecting prognosis in patients with locally advanced and advanced esophageal cancer receiving definitive radiotherapy in plateau regions

Variables

Univariate analysis

Multivariate analysis

HR

95.0%CI

p-value

HR

95.0%CI

p-value

Age(years)

0.794

0.590–1.070

0.130

   

< 60

≥ 60

BMI

0.950

0.902-1.000

0.051

0.946

0.898–0.997

0.037

ECOG performance status

1.230

0.897–1.686

0.199

   

ECOG 0

ECOG 1

ECOG 2

The length of the lesion(cm)

0.995

0.937–1.057

0.868

   

Tumor location

0.861

0.725–1.022

0.087

0.900

0.756–1.070

0.233

Cervical

Upper-thoracic

Mid-thoracic

Lower-thoracic

Adjuvant therapy

1.555

1.150–2.103

0.004

1.385

0.989–1.941

0.058

Yes

No

Clinical stages

0.931

0.763–1.135

0.477

   

III

IVA

IVB

M

0.953

0.657–1.384

0.802

   

0

1

N position

Mediastinal

1.049

0.729–1.509

0.795

   

Supraclavicular

0.825

0.607–1.120

0.217

   

Celiac

0.941

0.695–1.273

0.692

   

Concurrent chemotherapy

0.861

0.638–1.162

0.327

   

Yes

No

Immunotherapy

1.520

1.094–2.111

0.012

1.280

0.885–1.851

0.189

Yes

No

Radiotherapy dose

0.987

0.725–1.344

0.934

   

High dose (> 54 Gy)

Standard dose (≤ 54 Gy)

PTV (cm3)

1.000

0.999–1.001

0.617

   

CTV (cm3)

1.000

0.999–1.001

0.528

   

GTV (cm3)

1.001

0.997–1.005

0.643

   

GTVnd (cm3)

1.005

0.998–1.012

0.184

   

New (cm3)

1.000

0.999–1.002

0.670

   
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