Fig. 2

MRI images and analysis of IDD model and drugs treated IDD model before and after modeling. PDE4 inhibitor reduces the progression of lesions in the IDD model. Orange arrow points out the needle puncture site; (A) Typical MRI representative images (B) MRI score diagram. Data shown are means ± SEM of n = 5. * p < 0.05, ** p < 0.01, ***p < 0.001.