Fig. 5 | Scientific Reports

Fig. 5

From: PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration

Fig. 5

Effect of ferroptosis of nucleus pulposus through Nrf2 signalling pathway in IDD patients. The expression of ACSL4, TFRC, pNrf2 were determined by nucleus pulposus tissue of the IDD patients by western blotting. (A) Representative images of ACSL4, TFRC and pNrf2 (B) densitometric analysis in the IDD patients with different degrees of lesions. Data shown are means ± SEM of n = 3. *p < 0.05, **p < 0.01, ***p < 0.001.

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