Table 3 Sensitivity analyses: HRs (95% CIs) for all-cause mortality among depression participants according to frailty score.

From: Association between frailty index and mortality in depressed patients: results from NHANES 2005–2018

Characteristics

Frailty score

P-trend

per-unit increase in the frailty score (Ln-transformed)

Tertile1 (0.089,0.236)

Tertile 2 (0.236,0.343)

Tertile 3 (0.343,0.743)

Excluding participant who had a history of CVD at baseline

 Model 1

1 (reference)

2.03 (1.33 ~ 3.11)

3.2 (2.1 ~ 4.89)

< 0.001

3.76 (2.38 ~ 5.92)

 Model 2

1 (reference)

2.06 (1.34 ~ 3.16)

2.98 (1.93 ~ 4.59)

< 0.001

3.26 (2.04 ~ 5.2)

 Model 3

1 (reference)

1.94 (1.26 ~ 2.99)

2.65 (1.7 ~ 4.12)

< 0.001

2.84 (1.75 ~ 4.6)

Excluding participant who had a history of Cancer at baseline

 Model 1

1 (reference)

1.95 (1.27 ~ 2.97)

3.48 (2.33 ~ 5.19)

< 0.001

4.35 (2.94 ~ 6.45)

 Model 2

1 (reference)

1.95 (1.28 ~ 2.99)

2.97 (1.96 ~ 4.5)

< 0.001

3.65 (2.4 ~ 5.55)

 Model 3

1 (reference)

1.79 (1.16 ~ 2.76)

2.59 (1.69 ~ 3.97)

< 0.001

3.11 (2.02 ~ 4.8)

Multiple imputation of missing data

 Model 1

1 (reference)

1.87 (1.28 ~ 2.72)

3.38 (2.36 ~ 4.83)

< 0.001

3.56 (1.66 ~ 7.62)

 Model 2

1 (reference)

1.85 (1.25 ~ 2.72)

3.02 (2.07 ~ 4.4)

< 0.001

3.38 (1.53 ~ 7.49)

 Model 3

1 (reference)

1.74 (1.17 ~ 2.59)

2.62 (1.77 ~ 3.87)

< 0.001

2.85 (1.25 ~ 6.47)

  1. According to the ICD-10 criteria, CVD mortality was defined as I00-I09, I11, I13, and I20-I51, and cancer mortality was defined as C00-C97. Model 1 was adjusted for age, race, and gender. Model 2 was additionally adjusted for marital status, BMI, PIR group, educational level, smoking status, PA total time, and alcohol intake. Model 3 was additionally adjusted for diabetes, hyperlipidemia, and hypertension. CVD, cardiovascular disease.
Back to article page