Fig. 2 | Scientific Reports

Fig. 2

From: Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice

Fig. 2

Profiles of purine metabolism in Hprt(high)Xdh(− / −)Slc23a4(− / −) and Hprt(high)Xdh(+ / −)Slc23a4(− / −) mice that were fed a normal diet or a low-purine purified diet. (A) urinary hypoxanthine/creatinine ratio, (B) urinary xanthine/creatinine ratio, (C) total urinary purine/creatinine ratio. The data represent the means ± SDs. *p < 0.05, **p < 0.01 vs. the Xdh(− / −) MRA group; #p < 0.05, ##p < 0.01 vs. the Xdh(− / −) AIN group; ††p < 0.01 vs. the Xdh(+ / −) MRA group. P values were calculated via one-way ANOVA. Normal diet; MRA. Low-purine purified diet; AIN.

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