Table 1 The baseline characteristics of participants.

From: Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes

HSI

Q1(≤ 29.84)

Q2(29.84 to ≤ 33.06)

Q3(33.06 to ≤ 36.76)

Q4(> 36.76)

P-value

Participants

2810

2810

2809

2812

 

Gender

    

 < 0.001

 Male

1688 (60.07%)

1779 (63.31%)a

1900 (67.64%)ab

2145 (76.28%)abc

 

 Female

1122 (39.93%)

1031 (36.69%)

909 (32.36%)

667 (23.72%)

 

Age(years)

49.35 ± 15.69

52.28 ± 13.91a

51.26 ± 13.21ab

46.87 ± 12.48abc

 < 0.001

Drinking status

    

 < 0.001

 Current-drinker

924 (32.88%)

880 (31.32%)

815 (29.01%)a

673 (23.93%)abc

 

 Ex-drinker

408 (14.52%)

409 (14.56%)

467 (16.63%)

543 (19.31%)

 

 Never- drinker

1478 (52.60%)

1521 (54.13%)

1527 (54.36%)

1596 (56.76%)

 

Smoking status

    

 < 0.001

 Current-smoker

445 (15.84%)

511 (18.19%)a

564 (20.08%)a

700 (24.89%)abc

 

 Ex-smoker

123 (4.38%)

116 (4.13%)

112 (3.99%)

134 (4.77%)

 

 Never-smoker

2242 (79.79%)

2183 (77.69%)

2133 (75.93%)

1978 (70.34%)

 

Family history of diabetes

    

0.003

 No

2761 (98.26%)

2736 (97.37%)a

2753 (98.01%)

2725 (96.91%)ac

 

 Yes

49 (1.74%)

74 (2.63%)

56 (1.99%)

87 (3.09%)

 

SBP (mmHg)

123.84 ± 17.88

127.18 ± 18.08a

128.66 ± 17.36ab

130.70 ± 16.83abc

 < 0.001

DBP (mmHg)

75.34 ± 10.78

77.79 ± 11.19a

79.27 ± 11.05ab

81.29 ± 10.82abc

 < 0.001

BMI (kg/m2)

21.22 ± 1.83

23.97 ± 1.62a

25.76 ± 1.88ab

28.34 ± 2.87abc

 < 0.001

ALT (U/L)

14 (11.1–18)

19 (14.9–24)a

25 (19–32.3)ab

39.6 (29–58.9)abc

 < 0.001

AST (U/L)

22 (19.00–26)

23 (19.22–27)a

24 (20–29.1)ab

28 (23–36)abc

 < 0.001

HSI (mmol/L)

27.33 ± 1.86

31.45 ± 0.94a

34.80 ± 1.06ab

40.65 ± 3.49abc

 < 0.001

TG (mmol/L)

1.00 (0.70–1.41)

1.31 (0.91–1.97)a

1.56 (1.09–2.30)ab

1.88 (1.30–2.73)abc

 < 0.001

HDL-C (mmol/L)

1.44 ± 0.29

1.36 ± 0.33a

1.31 ± 0.28ab

1.26 ± 0.28abc

 < 0.001

LDL-C (mmol/L)

2.76 ± 0.66

2.90 ± 0.71a

2.93 ± 0.69a

2.98 ± 0.73abc

 < 0.001

TC (mmol/L)

4.80 ± 0.91

4.99 ± 0.96a

5.04 ± 0.93a

5.12 ± 0.96abc

 < 0.001

BUN (mmol/L)

4.95 ± 1.32

5.05 ± 1.22a

5.13 ± 1.30ab

5.03 ± 1.21ac

 < 0.001

Scr (umol/L)

72.47 ± 16.29

73.80 ± 16.32a

74.47 ± 16.43a

75.58 ± 15.25abc

 < 0.001

FPG (mmol/L)

5.90 ± 0.29

5.93 ± 0.31a

5.96 ± 0.32ab

6.00 ± 0.33abc

 < 0.001

  1. Values are n (%) or mean ± SD or median (quartile).
  2. HSI: hepatic steatosis index; SBP: systolic blood pressures; DBP: diastolic blood pressures; BMI: body mass index; AST: aspartate aminotransferase; ALT: alanine aminotransferase; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TC: total cholesterol; TG: triglycerides; Scr: serum creatinine; BUN: blood urea nitrogen; FPG: fasting plasma glucose.
  3. aRepresents other groups (Q2, Q3, Q4) compared with Q1, P < 0.05.
  4. bRepresents other groups (Q3, Q4) compared with Q2, P < 0.05.
  5. cRepresents other groups (Q4) compared with Q3, P < 0.05.
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