Table 4 Relationship between HSI levels and reversion to normoglycemia from Pre-DM in different sensitivity analyses.

From: Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes

Exposure

Model 4 (HR,95%CI, P)

Model 5 (HR,95%CI, P)

Model 6 (HR,95%CI, P)

HSI (per 1-SD)

0.89 (0.86, 0.93) < 0.0001

0.91 (0.88, 0.95) < 0.0001

0.92 (0.89, 0.95) < 0.0001

HSI

 Q1

Ref

Ref

 

 Q2

0.87 (0.79, 0.96) 0.0042

0.87 (0.80, 0.95) 0.0021

0.88 (0.82, 0.95) 0.0015

 Q3

0.88 (0.79, 0.97) 0.0102

0.89 (0.80, 0.98) 0.0134

0.88 (0.81, 0.96) 0.0028

 Q4

0.75 (0.67, 0.84) < 0.0001

0.81 (0.72, 0.91) 0.0002

0.80 (0.73, 0.88) < 0.0001

P for trend

 < 0.0001

0.0002

 < 0.0001

  1. Model 4 was sensitivity analysis in participants without TC>5.2mmol/L. We adjusted age, gender, SBP, DBP, drinking status, family history of diabetes, smoking status, FPG, HDL-C, BUN, LDL-C, Scr, and TG.
  2. Model 5 was sensitivity analysis in participants without TG>1.7 mmol/L. We adjusted age, gender, SBP, DBP, drinking status, family history of diabetes, smoking status, FPG, HDL-C, BUN, LDL-C, Scr, and TG.
  3. Model 6 was sensitivity analysis in participants without HSI outliers. We adjusted age, gender, SBP, DBP, drinking status, family history of diabetes, smoking status, FPG, HDL-C, BUN, LDL-C, Scr, and TG.
  4. HSI: hepatic steatosis index; HR, hazard ratios; CI, confidence, Ref: reference.