Fig. 3
From: CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis
CRIP1 overexpression inhibits proliferation and invasion of cutaneous melanoma cells. RT-qPCR (A) and WB (B) confirmed that CRIP1 was stably overexpressed in SK-MEL-2 and A375 cells. EDU cell proliferation assay (C) and colony formation assay (D) were performed to assess the proliferative capacity of CRIP1 overexpressed cutaneous melanoma cells (Fig. C scale bar 50 μm). (E) Wound healing assay to assess the migration ability of CRIP1 overexpressing cutaneous melanoma cells (scale bar 100 μm). (F) Transwell invasion assay to assess the invasive ability of CRIP1 overexpressing cutaneous melanoma cells (scale bar 50 μm). (G) WB assay to assess the apoptosis of CRIP1 overexpressing cutaneous melanoma cells. Data are shown as SD ± mean.
