Table 1 The effects of DMF (dimethyl fumarate) on the infiltration of inflammatory cells and congestion in PQ (paraquat)-induced hepatotoxicity in mice.

From: Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities

Groups

Congestion of vessels

Infiltration of inflammatory cells

Control

0.13 ± 0.04

0.11 ± 0.03

DMF100

0.09 ± 0.01

0.08 ± 0.01

PQ

2.9 ± 0.03 ***

2.6 ± 0.35 ***

DMF10 + PQ

1.6 ± 0.24 ***#

1.4 ± 0.28***#

DMF30 + PQ

1.1 ± 0.026**##

0.73 ± 0.16**##

DMF100 + PQ

0.23 ± 0.11*###

0.27 ± 0.09*###

  1. *Significant difference compared to the control group (*P < 0.05, **P < 0.01, and ***P < 0.001).
  2. #Significant difference compared to the PQ group (#P < 0.05, ##P < 0.01, and ###P < 0.001)
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