Fig. 6 | Scientific Reports

Fig. 6

From: Ankrd1 as a potential biomarker for the transition from acute kidney injury to chronic kidney disease

Fig. 6

Expression patterns and New PT2 subcluster function of hub genes. Expression distribution (A) and dynamics (B) in different branch of hub genes on the trajectories. Violin plot (the single-cell dataset GSE139107) (C) and boxplot (the bulk RNA-seq dataset GSE98622) (D) of the Ankrd1 and Sema5a genes expression at different sample timepoints. (E) UMAP displaying the clustering of New PT2 cells. (F) Expression of Ankrd1 and Sema5a genes in New PT2 subclusters. (G) Pseudotime trajectory of New PT2 cells colored by subclusters from 0 to 8. (H) Dotplot of GO enrichment analysis of New PT2 subcluster. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. Sham group.

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