Table 2 Descriptive characteristics of postnatal mismatch groups.

From: Early life factors and variation in adult kidney function in the Swedish LifeGene cohort

 

Group 1

Low BWz + Lower-than-average FMI

(N = 392)

Group 2

Normal BWz + Lower-than-average FMI

(N = 5298)

Group 3

High BWz + Lower-than-average FMI

(N = 397)

Group 4

Low BWz + Higher-than-average FMI

(N = 336)

Group 5

Normal BWz + Higher-than-average FMI

(N = 5257)

Group 6

High BWz + Higher-than-average FMI

(N = 487)

P-value between groups

Early life factors

GA, weeks

40 (2)

40 (2)

40 (2)

40 (2)

40 (2)

40 (2)

< 0.001

BW, g

2685 (391)

3490 (425)

4420 (353)

2778 (333)

3504 (430)

4388 (351)

< 0.001

BL, cm

48 (2)

50 (2)

53 (2)

48 (2)

50 (2)

53 (2)

< 0.001

HC, cm

33 (2)

35 (2)

36 (2)

33 (2)

35 (2)

36 (1.4)

< 0.001

BWz

-2.66 (0.69)

-0.04(0.96)

2.76 (0.78)

-2.63 (0.62)

-0.01 (0.97)

2.69 (0.70)

< 0.001

Adult life factors

Age, years

29 (6)

28 (6)

28 (5)

32 (6)

30 (6)

30 (6)

< 0.001

Sex, women

282 (71.9)

3074 (58.0)

161 (40.6)

224 (66.7)

3077 (58.5)

211 (43.3)

< 0.001

BMI, kg/m2

20.8 (1.7)

21.4 (1.9)

22.2 (2.0)

25.4 (3.2)

25.5 (3.1)

26.1 (3.2)

< 0.001

FMI, kg/m2

4.2 (2.0)

3.9 (2.1)

3.5 (2.2)

6.9 (2.3)

6.8 (2.7)

6.4 (2.9)

< 0.001

Diabetes history, yes

2 (0.5)

11 (0.2)

0 (0.0)

0 (0.0)

17 (0.3)

3 (0.6)

0.280

Kidney disease history, yes

4 (1.0)

27 (0.5)

1 (0.3)

5 (1.5)

48 (0.9)

6 (1.2)

0.039

eGFRcr, mL/min/1.73m2

86 (15)

83 (14)

78 (14)

84 (15)

83 (15)

81 (16)

< 0.001

CKD, yes

17 (4.3)

180 (3.4)

20 (5.0)

6 (1.8)

231 (4.4)

29 (6.0)

0.003

SBP, mmHg

111 (11)

113 (11)

114 (11)

114 (11)

116 (11)

117 (11)

< 0.001

DBP, mmHg

67 (8)

68 (8)

68 (9)

69 (9)

70 (9)

71 (9)

< 0.001

MAP, mmHg

82 (8)

83 (8)

83 (8)

84 (9)

85 (9)

86 (8)

< 0.001

WC, cm

72 (6)

75 (7)

78 (7)

83 (10)

85 (10)

88 (10)

< 0.001

  1. Abbreviations: BMI, body mass index; FMI, fat mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; WC, waist circumference; GA, gestational age, BW, birth weight; BL, birth length; HC, head circumference; BWz, birth weight sex-specific z-score; eGFRcr, estimated creatinine-based glomerular filtration rate; eGFRcys, estimated cystatin C based glomerular filtration rate; CKD, chronic kidney disease where eGFRcr is below 60 mL/min/1.73m2.
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