Table 2 Multivariable analysis of continuous GNRI vs. poor prognosis.

From: Impact of geriatric nutritional risk index and diabetes mellitus on prognosis in ischaemic heart failure with reduced ejection fraction

Outcome

Overall population

HR (95% CI)

P Value

All-cause deatha

 GNRI

0.967 (0.932–1.003)

0.070

 Age, years

1.036 (1.014–1.059)

0.002

 Prior arrhythmia, n (%)

1.046 (0.657–1.665)

0.850

 NYHA, n (%)

1.212 (0.951–1.546)

0.120

 Cholinesterase, U/L

1.060 (0.922–1.218)

0.411

 BNP, pg/mL

1.000 (1.000–1.001)

0.005

 Beta-blocker, n (%)

0.574 (0.364–0.905)

0.017

 TPD, %

1.003 (0.990–1.016)

0.679

 LVEF, %

0.946 (0.917–0.976)

0.001

Cardiac deathb

 GNRI

0.950 (0.914–0.987)

0.009

 Age, years

1.034 (1.010–1.060)

0.006

 NYHA, n (%)

1.261 (0.964–1.648)

0.09

 Cholinesterase, U/L

1.098 (0.945–1.277)

0.223

 BNP, pg/mL

1.000 (1.000–1.000)

0.229

 Beta-blocker, n (%)

0.560 (0.341–0.920)

0.022

 TPD, %

1.002 (0.988–1.016)

0.803

 LVEF, %

0.928 (0.894–0.960)

< 0.001

  1. BNP brain natriuretic peptide, DM diabetes mellitus, GNRI geriatric nutritional risk index, HR hazard ratio, LVEF left ventricular ejection fraction, NYHA New York Heart Association, TPD total perfusion defects.
  2. aVariables with P < 0.05 in univariable analysis were used as covariates for adjustment (including age, NYHA, prior arrhythmia, cholinesterase, BNP, beta-blocker, TPD, and LVEF).
  3. bVariables with P < 0.05 in univariable analysis were used as covariates for adjustment (including age, NYHA, cholinesterase, beta-blocker, BNP, TPD, and LVEF).
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