Table 1 General characteristics of the study subjects.

From: Accuracy of blood heparin-binding protein (HBP) for diagnosis bacteremia in patients with sepsis

Variable

Bacteria(n = 57)

Control(n = 89)

P value

Sex (n, % male)

43(75.44)

54(60.67%)

0.07

Age (year)

63.6 ± 17.02

63.18 ± 17.46

0.8

Causes of ICU admission (n)

Postoperative surgery

24

23

0.05

Multiple injuries

7

13

0.81

Respiratory disease

4

12

0.28

Digestive system disease

3

10

0.08

Heatstroke

3

5

0.99

Central nervous system disease

2

4

0.99

Cardiovascular disease

2

3

0.99

Other disease

12

16

0.67

Main comorbidities (n)

MODS

22

35

0.99

respiratory failure

6

11

0.80

renal failure

3

6

0.99

cardiac insufficiency

1

2

0.99

pulmonary infection

3

6

0.99

perforation of the digestive tract

1

4

0.65

ileus

1

2

0.99

Other comorbidities

20

23

0.26

HBP (ng/mL)

204.13 ± 87.30

81.43 ± 61.53

p < 0.001

PCT (ng/mL)

15.00 ± 40.35

3.89 ± 12.12

p < 0.01

IL-6 (pg/ml)

462.7 ± 995.58

202.8 ± 319.14

p < 0.05

WBC (10^9/L)

13.48 ± 7.95

11.14 ± 5.49

p < 0.05

CRP (mg/dl)

10.48 ± 7.27

5.816 ± 5.05

p < 0.001

Neutrophil

0.87 ± 0.08

0.83 ± 0.13

0.057

BNP (pg/ml)

6651.27 ± 10420.44

4693.95 ± 9458.49

0.26

AST

93.12 ± 320.366

78.98 ± 220.46

0.76

ALT

77.61 ± 243.24

66.82 ± 113.06

0.73

Creatinine

129.9 ± 154.32

113 ± 127.58

0.49

Lactate

1.685 ± 1.47

1.689 ± 1.67

0.98

Glucose

8.285 ± 3.10

7.931 ± 2.63

0.48

ICU days

20(2 ~ 374)

20(1 ~ 406)

0.58

ICU mortality (n, %)

13(22.4)

18(20.2)

0.84

CRRT

17(29.82)

24(26.97)

0.71

Mechanical ventilation

52(91.23)

72(80.90)

0.1

SOFA

9.79 ± 4.78

10.36 ± 4.23

0.46

APACHE II

19.21 ± 6.94

20.93 + 6.80

0.15

  1. Notes HBP heparin-binding protein, PCT procalcitonin, IL-6 Interleukin 6, CRP C-reactive protein, WBC white blood counts, BNP brain natriuretic peptide (NT-pro), AST aspartate aminotransferase, ALT alanine aminotransferase, ICU Intensive care medicine, CRRT continuous renal replacement therapy, SOFA sequential organ failure assessment, APACHE acute physiology and chronic health evaluation (APACHE) II, MODS Multiple organ dysfunction syndrome.