Table 1 Concordance between ELISA and luciferase-based assay results, with patient and control demographics.
ID | Diagnosis | Age | Sex | WNV-NTAbs | IFN-α2 10 RLA Ratio (%) | IFN-β 10 RLA Ratio (%) | IFN-ω 10 RLA Ratio (%) | IFN-α2 100 RLA Ratio (%) | IFN-ω 100 RLA Ratio (%) | IFN-β 1 RLA Ratio (%) | OD Anti-α2_ELISA | OD Anti-β_ELISA | OD Anti-ω_ELISA | Summary_results_ELISA | AAb + /- (ELISA) | IFN-I-NTAbs | IFN-I-NTAbs ARPE Assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S04 | WNND | 75 | M | < 1:10 | 2.5 | 28.0 | 2.8 | 4.6 | 2.6 | 10.2 | 3.5 | 0.5 | 0.5 | α2 | AAb + | Pos | α2 Pos > 10,000 pg/mL |
S06 | WNND | 71 | M | 1:10 | 0.6 | 16.5 | 2.2 | 1.6 | 2.6 | 55.0 | 3.4 | 0.1 | 0.3 | α2 | AAb + | Pos | α2 Pos > 10,000 pg/mL |
S07 | WNND | 79 | F | 1:10 | 1.6 | 47.3 | 1.3 | 6.5 | 11.5 | 18.4 | 3.5 | 0.6 | 2.0 | α2;β;ω | AAb + | Pos | α2 Pos > 500 pg/mL |
S10 | WNND | 72 | M | 1:20 | 2.8 | 168.2 | 3.3 | 11.8 | 11.4 | 88.3 | 3.5 | 0.3 | 1.1 | α2,ω | AAb + | Pos | α2 Pos > 10,000 pg/mL |
S11 | WNND | 62 | M | 1:40 | 2.2 | 84.6 | 2.7 | 12.5 | 7.0 | 34.3 | 3.5 | 0.4 | 1.0 | α2,ω | AAb + | Pos | α2 Pos > 10,000 pg/mL |
S18 | WNND | 90 | M | 1:40 | 2.0 | 68.4 | 1.3 | 3.3 | 2.8 | 57.3 | 2.3 | 0.5 | 1.6 | α2,ω | AAb + | Pos | ω Pos > 500 pg/mL |
S22 | WNND | 93 | F | 1:10 | 1.3 | 48.1 | 1.3 | 3.8 | 3.5 | 10.2 | 1.9 | 1.1 | 1.0 | α2;β;ω | AAb + | Pos | ω Pos > 500 / β Pos > 100 pg/mL |
S23 | WNND | 71 | F | 1:20 | 18.7 | 74.3 | 1.3 | 3.5 | 3.2 | 96.9 | 0.6 | 0.4 | 1.7 | α2,ω | AAb + | Pos | ω Pos > 500 pg/mL |
S24 | WNND | 78 | F | < 1:10 | 2.5 | 90.6 | 1.6 | 4.2 | 4.1 | 100.0 | 2.3 | 0.4 | 1.4 | α2,ω | AAb + | Pos | ω Pos > 500 pg/mL |
S21 | WNND | 56 | M | 1:40 | 57.6 | 74.9 | 47.4 | 55.0 | 44.8 | 70.2 | 0.1 | 0.1 | 1.1 | – | No AAb | Neg | Neg |
S25 | WNND | 61 | F | < 1:10 | 78.3 | 67.5 | 56.8 | 67.2 | 52.1 | 68.4 | 0.3 | 0.2 | 0.1 | – | No AAb | Neg | Neg |
N1 | Healthy_blood_donor | 61 | M | 1:10 | 81.6 | 76.4 | 66.1 | 71.4 | 72.6 | 73.0 | 0.3 | 0.5 | 0.2 | – | No AAb | Neg | Neg |
N2 | Healthy_blood_donor | 30 | F | 1:40 | 50.8 | 49.3 | 46.3 | 37.6 | 32.3 | 44.9 | 0.3 | 0.4 | 0.3 | – | No AAb | Neg | Neg |
N4 | Healthy_blood_donor | 55 | M | 1:10 | 54.3 | 93.5 | 58.6 | 54.7 | 30.5 | 67.4 | 0.2 | 0.2 | 0.1 | – | No AAb | Neg | Neg |
