Table 1 Identification of pro-inflammatory and pro-resolving mediators from human M2-like macrophages exposed to SiO2 NPs and E. Coli bacteria*.

From: SiO2 nanoparticles as disruptors of endogenous resolution mechanisms of inflammatory responses that exacerbate pneumonia

 

PGE2

LTB4

RvD5

M2 Macrophage + Vehicle

8.26

20.05

0.62

M2 Macrophage + SiO2

27.70

297.18

17.74

M2 Macrophage + SiO2 + E. Coli

71.46

2636.87

9.86

  1. *Results are expressed as pg/10 × 106 cells incubated with SiO2 NPs (10 µg/mL) alone and with E. Coli. Incubations were carried out for 30 min, pH 7.45, 37 °C in DPBS+/+ containing both Ca2+ and Mg2+ (n = 5 healthy human donors).
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