Fig. 1
From: Intratumoral administration of mRNA COVID-19 vaccine delays melanoma growth in mice
mRNA-1273 vaccine immunization increases CD8 + T cell infiltration at the injection site and is uptaken by B16F10 melanoma cells. Flow cytometry of CD8+ T cells in the (A) muscle of injection site and (B) draining lymph node 24 h post immunization with 10 µg of mRNA-1273 or PBS control (n = 5 mice/group, n = 10 mice total). Data shown as mean (SD); unpaired student t test, **p = 0.0081, ***p < 0.001. (C) Cropped Western blot of spike protein in B16F10 cells at different timepoints after incubation with 200 µL (40 µg) mRNA-1273 (n = 3 independent experiments). Original full blots are presented in Supplementary Fig. 14.
