Fig. 3
From: Gait impairment associated with neuroimaging biomarkers in Alzheimer’s disease
Schematic representations of path models illustrating relationships between global amyloid-β deposition, regional cortical thickness, total cognition, and gait impairment. Red paths indicate significant path coefficients. (A) Models incorporating cortical thickness in the middle temporal gyrus demonstrating good fit for velocity and step length. (B) Models incorporating cortical thickness in the middle temporal gyrus demonstrating good fit for swing time and double support percentages. (C) Models incorporating cortical thickness in the inferior parietal lobule and precuneus demonstrating good and satisfactory fits with all four gait parameters. (D) Models incorporating cortical thickness in the insula demonstrating satisfactory fit with step length. Amy, amyloid-β; SUVR, standardized uptake ratio value; CTh, cortical thickness; Cog; cognitive score; Gait, gait parameter; MTG, middle temporal gyrus; IPL, inferior parietal lobule; Swing %, Swing percentage; Double support %, double support percentage.
