Fig. 2 | Scientific Reports

Fig. 2

From: Identifying robust biomarkers for the diagnosis and subtype distinction of inflammatory bowel disease through comprehensive serum metabolomic profiling

Fig. 2

Serum metabolite distributions and discriminatory analysis in inflammatory bowel disease subtypes versus normal controls. (a) Principal Component Analysis (PCA) and (b) Partial Least Squares-Discriminant Analysis (PLS-DA) score plots visualization showcases the metabolic distinctions. (c) A heatmap visualization of the identified serum metabolites derived from Gas Chromatography-Time of Flight Mass Spectrometry (GC-TOF-MS) dataset. (d,e) Boxplots of tryptophan metabolism-related metabolites and ratio of primary and secondary bile acids. Significantly altered serum metabolites indicated by asterisk (*p value < 0.05, ** p value < 0.01, *** p value < 0.001, **** p value < 0.0001).

Back to article page