Fig. 3

Prognostic value of the IRGPI for patients with HCC. (A) OS was shorter in the IRGPI-high group than in the IRGPI-low group. Patients in the IRGPI-high subgroup had significantly shorter overall survival than those in the IRGPI-low subgroup did, indicating that a higher IRGPI score is associated with a worse prognosis. (B) ROC curves for 1-, 3-, and 5-year prognostic prediction by the IRGPI. The ROC curves demonstrate the predictive accuracy of the IRGPI for 1-, 3-, and 5-year survival outcomes. The area under the curve (AUC) values were 0.850 for 1-year survival, 0.779 for 3-year survival, and 0.857 for 5-year survival, indicating strong predictive performance of the IRGPI over these timeframes. (C) Calibration curves for the ability of the IRGPI to predict 1-, 3-, and 5-year prognoses. The calibration curves demonstrated the agreement between the predicted and observed survival outcomes at 1, 3, and 5 years. The C-index values for IRGPI prediction were 0.912, 0.829, and 0.813 for 1-, 3-, and 5-year survival, respectively, indicating a high degree of accuracy in prognostic prediction. (D) Nomogram for predicting 1-, 3-, and 5-year prognoses on the basis of the IRGPI and MVI. A nomogram incorporating the IRGPI and other prognostic factors, such as microvascular invasion (MVI), was constructed to predict patient survival at 1, 3, and 5 years. The nomogram provides a visual tool for clinicians to estimate individual patient survival probability on the basis of these combined factors.