Table 1 Comparison of baseline data among the control, TPOAb (+), and TgAb (+) groups.

From: Serum metabolomic analysis in patients with Hashimoto’s thyroiditis positive for TgAb or TPOAb: a preliminary study

 

Group

P-value

G1vs.G2 comparison

G1vs.G3 comparison

G2vs.G3 comparison

Control ( G1 )

TPOAb ( + ) ( G2 )

TgAb ( + ) ( G3 )

P-value

P-value

P-value

Sex, M/F

0/14

0/14

0/4

–

–

–

–

Age, y

38.65 ± 2.80

38.43 ± 2.67

44.25 ± 5.00

0.583

–

–

–

TSH, mIU/L

2.14 ± 0.23

14.14 ± 10.48

13.91 ± 6.90

0.462

–

–

–

FT3, pmol/l

4.97 ± 0.13

4.37 ± 0.30

4.20 ± 0.11

0.103

–

–

–

FT4, pmol/l

14.95 ± 0.49

13.48 ± 1.08

12.15 ± 1.12

0.211

–

–

–

TgAb, U/mL

15.00 (15.00,15.00)

19.99 (15.00,33.47)

267.74 (180.40,308.50)

< 0.0001

0.897

< 0.0001

< 0.0001

TPOAb, U/mL

29.15 (28.00,34.61)

1300.00 (768.39,1300.00)

31.34 (28.00,45.08)

< 0.0001

< 0.0001

1.000

< 0.0001

  1. Data are presented as means ± standard deviations for continuous variables and as n (%) for categorical variables. TgAb and TPOAb levels are expressed as medians (P25-P75). Group differences were assessed using analysis of variance (ANOVA) or the Kruskal-Wallis test. To account for multiple comparisons, the Bonferroni correction was applied, with a significance threshold set at 0.05/3. A p-value of less than 0.017 was considered statistically significant.
  2. Normal Ranges:
  3. TSH, mIU/L 0.38–4.34; FT3, pmol/L 2.77–6.31; FT4, pmol/L10.44-24.38;
  4. TgAb, U/mL 0–60; TPOAb, U/mL 0–60.
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