Table 2 DNA methylation levels(%) of targets between cases and controls (mean ± SD).

From: Validation of DNA methylation and transcriptional characteristics in CCL5 and CXCL8 genes in autoimmune thyroiditis with varying iodine levels

Gene

Target

Case

Control

Group.diff

P

CCL5

CCL5_1

96.3 ± 0.8

96.2 ± 0.8

< 0.1

0.328

CCL5_2

80.2 ± 6.2

82.1 ± 4.9

−1.9

0.002**

CXCL8

CXCL8_1

24.6 ± 1.1

25.0 ± 1.3

−0.4

0.003**

CXCR5

CXCR5_1

95.4 ± 0.4

95.4 ± 0.5

< 0.1

0.280

CXCL14

CXCL14_1

2.8 ± 1.1

2.7 ± 0.8

0.1

0.269

  1. Group.diff = The methylation level of case−The methylation level of control.
  2. *P < 0.05, **P < 0.01, t test.