Table 3 Comparisons of ∆ value of observing indexes before and after treatment between two groups(\(\overline x\)±s)

From: Negative pressure wound therapy promotes wound healing by down-regulating miR-155 expression in granulation tissue of diabetic foot ulcers

Variables

NPWT (n = 40)

Non-NPWT (n = 20)

P value

∆ULA, cm2

-2.75 ± 0.28

-1.11 ± 0.23

0.043

∆FPG, mmol/L

-2.78 ± 0.16

-2.39 ± 0.14

0.586

∆ABI

0.01 ± 0.01

0.01 ± 0.02

0.893

∆CRP, mg/dl

-21.57 ± 3.87

-8.12 ± 0.24

< 0.001

∆WBC, ×109

-2.69 ± 0.18

-1.02 ± 0.24

0.031

∆ESR, mm/h

-5.73 ± 1.67

-4.98 ± 1.22

0.712

∆Hb, g/L

-0.98 ± 0.08

-0.93 ± 0.07

0.746

∆Alb, g/L

-0.45 ± 0.11

-0.43 ± 0.09

0.801

∆T-IL-1β, pg/ml

-9.53 ± 0.98

-4.42 ± 0.69

0.027

∆T-IL-6, pg/ml

-39.28 ± 4.83

-20.87 ± 5.12

0.007

∆T-IL-4, pg/ml

5.28 ± 0.85

3.27 ± 0.36

0.047

∆IL-10, pg/ml

11.42 ± 0.72

3.69 ± 0.95

0.002

∆T-miR-155

-2.69 ± 0.42

-0.81 ± 0.23

0.009

∆T-FGF7

0.31 ± 0.12

0.17 ± 0.08

0.038

  1. Notes: Data was presented as mean ± SD.
  2. Abbreviations: NPWT, negative-pressure wound therapy group; Non-NPWT, without receiving NPWT group; ULA, ulcer area; FPG, fasting plasma glucose; ABI, ankle brachial index; CRP, C-reactive protein; WBC, white blood cell; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; Alb, albumin; IL, interleukin; T-IL-1β, concentration of IL-1β in the supernatant of granulation tissue; T-IL-6, concentration of IL-6 in the supernatant of granulation tissue; T-IL-4, concentration of IL-4 in the supernatant of granulation tissue; T-IL-10, concentration of IL-10 in the supernatant of granulation tissue; T-miR-155, miR-155 expression in wound granulation tissue; T-FGF7, FGF7 protien expression in wound granulation tissue;∆, the change value of various index before and after treatment.
Back to article page