Table 4 Spearman’s correlation analysis of ∆T-miR-155 with ∆ value of other observing indexes in two groups.

From: Negative pressure wound therapy promotes wound healing by down-regulating miR-155 expression in granulation tissue of diabetic foot ulcers

Variable

NPWT (n = 40)

Non-NPWT (n = 20)

ra

P

ra

P

△ULA, cm2

0.281

0.031

0.094

0.425

△FPG, mmol/L

0.203

0.072

0.187

0.098

△ABI

0.032

0.763

0.041

0.722

△CRP, mg/dl

0.311

0.007

0.145

0.142

△WBC, ×109

0.276

0.022

0.112

0.251

△ESR, mm/h

0.126

0.173

0.103

0.284

∆Hb, g/L

0.074

0.587

0.072

0.611

∆Alb, g/L

0.042

0.619

0.093

0.475

∆T-IL-1β, pg/ml

0.284

0.029

0.151

0.193

∆T-IL-6, pg/ml

0.335

0.004

0.179

0.118

∆T-IL-4, pg/ml

-0.236

0.035

-0.098

0.285

∆IL-10, pg/ml

-0.291

0.018

―0.106

0.229

∆T-FGF7

-0.483

< 0.001

―0.098

0.361

  1. Notes: aCorrelation coefficients and P values were determined using Pearson correlation analysis.
  2. Abbreviations: NPWT, negative-pressure wound therapy group; Non-NPWT, without receiving NPWT group; ULA, ulcer area; FPG, fasting plasma glucose; ABI, ankle brachial index; CRP, C-reactive protein; WBC, white blood cell; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; Alb, albumin; IL, interleukin; T-IL-1β, concentration of IL-1β in the supernatant of granulation tissue; T-IL-6, concentration of IL-6 in the supernatant of granulation tissue; T-IL-4, concentration of IL-4 in the supernatant of granulation tissue; T-IL-10, concentration of IL-10 in the supernatant of granulation tissue; T-miR-155, miR-155 expression in wound granulation tissue; T-FGF7, FGF7 protien expression in wound granulation tissue; ∆, the change value of various index before and after treatment.
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