Table 5 The relationship between ∆T-miR-155 and skin ulcer clinical features in NPWT group [(\(\overline x\)± s), n (%)]

From: Negative pressure wound therapy promotes wound healing by down-regulating miR-155 expression in granulation tissue of diabetic foot ulcers

 

NPWT

 

High change group(n = 16)

Low change group (n = 24)

P-value

Age, year

53.5 ± 10.7

54.7 ± 11.4

0.513

Sex

  

0.792

Male

10 (62.5)

14 (58.3)

 

Female

6 (37.5)

10 (41.7)

 

Ulcer area, cm2

10.5 ± 2.8

11.2 ± 3.2

0.327

Ulcer duration, week

7.7 ± 1.7

8.2 ± 1.9

0.386

Wagner grade

  

0.573

II

4 (25.0)

8 (33.3)

 

III

12 (75.0)

16 (66.7)

 

Outcome of ulcer after 4 weeks

  

0.028

Healing

5 (31.3)

16 (65.8)

 

Non-healing

11 (68.7)

8 (34.2)

 
  1. Notes: Data presented as mean ± SD or median with IQR.
  2. Abbreviations: NPWT, negative-pressure wound therapy group; ∆T-miR-155, the change value of miR-155 expression in wound granulation tissue before and after NPWT.
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