Fig. 3 | Scientific Reports

Fig. 3

From: Immunogenic cell death signature predicts survival and reveals the role of VEGFA + Mast cells in lung adenocarcinoma

Fig. 3

The role of the IRS in predicting the efficacy of immunotherapy. (A) The correlation between IRS and the expression of immuno-oncology target genes in seven independent lung adenocarcinoma datasets. (B–D) The distribution of IRS across different immune therapy responses (NR, nonresponder; R, responder). (B) GSE93157. (C) GSE35640. (D) GSE91061. (E–G) Stacked bar plots showed the proportions of responsive and nonresponsive patients in HIRS and LIRS. (E) GSE93157. (F) GSE35640. (G) GSE91061. (H–L) Kaplan-Meier curves showed the survival outcomes of patients classified as HIRS or LIRS in the immunotherapy cohort. (H) GSE93157. (I) Ravi A_2023. (J) Mariathasan S_2018. (K) PRJEB23709. (L) phs001493 (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001).

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