Fig. 3
Immunosuppression in ARDSKT reduces the inflammatory response caused by S100A12+ Mono subpopulation. (A) Single-cell atlas displaying the single-cell landscape of Mono. (B) Dot-line graph illustrating the abundance changes of different subpopulations within the Mono group. (C) Density plot showing the markers of Mono cell subpopulations. (D) Bar chart displaying the significantly enriched BP and KEGG signaling pathways of the Mono cell subpopulation. (E) The gene set enrichment analysis revealed the activated signaling pathways by S100A12+ Mono subpopulation. (F) Density chart plots showing the expression levels of inflammatory cytokines in Mono subpopulation. (G) Single-cell maps showing the progression trajectory and Monocle 3 pseudotime values of monocytes. (H) GRN plot shows the marker group modules of monocytes. (I) Activity of TFs in monocyte subtypes.
