Fig. 4 | Scientific Reports

Fig. 4

From: Immune dysregulation in COVID-19 induced ARDS in kidney transplant recipients revealed by single-cell RNA sequencing

Fig. 4

The decrease in the abundance of the CXCR4+ B subpopulation mediates the exacerbation of ARDS after renal transplantation. (A) Single-cell atlas displaying the single-cell landscape of B. (B) Density plot showing the markers of B cell subpopulations. (C). Stacked violin plots showing the expression of markers distinguishing B cell subpopulations. (D) Dot-line graph illustrating the abundance changes of different subpopulations within the B group. (E) Bar chart displaying the significantly enriched BP and KEGG signaling pathways of the B cell subpopulation. (F) The gene set enrichment analysis revealed the activated signaling pathways by CXCL4+ B subpopulation. (G) Single-cell atlas mapping of B cell progression trajectories and Monocle3 pseudotime values. (H) GRN graph showing the module of marker genes in B cell subtypes. (I) Activity of TFs in B cell subtypes.

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