Table 1 Questionnaire analysis.

From: Brain connectivity correlates of the impact of a digital intervention for individuals with subjective cognitive decline on depression and IL-18

 

PRE

POST

Change

p-value

Effect size*

N

17

CES-D

12.8 ± 7.7

9.5 ± 6.6

− 3.4 ± 4.0

0.004

− 0.829

GAD7

4.7 ± 4.4

3.3 ± 3.1

− 1.4 ± 2.9

0.063

− 0.484

MHC_SF

     

Total

45.9 ± 10.1

47.5 ± 10.2

1.5 ± 6.6

0.356

0.231

Emotional well-being

10.3 ± 2.7

10.8 ± 2.6

0.5 ± 2.2

0.326

0.246

Social well-being

12.8 ± 4.1

13.1 ± 4.6

0.3 ± 4.3

0.779

0.069

Psychological well-being

22.8 ± 4.9

23.5 ± 4.5

0.7 ± 2.9

0.332

0.243

SF-36

     

Physical functioning

83.5 ± 24.6

87.9 ± 21.3

4.4 ± 32.0

0.577

0.138

Physical limitations

79.4 ± 32.4

89.7 ± 17.3

10.3 ± 31.9

0.203

0.322

Emotional limitations

68.6 ± 42.0

80.4 ± 30.4

11.8 ± 42.4

0.269

0.278

Energy

62.1 ± 19.6

62.9 ± 22.1

0.9 ± 21.9

0.870

0.040

Emotional wellbeing

73.2 ± 14.2

70.4 ± 20.0

− 2.8 ± 20.9

0.586

− 0.135

Social function

86.8 ± 18.9

93.4 ± 16.7

6.6 ± 16.6

0.120

0.399

Pain domain

83.2 ± 15.8

85.0 ± 14.6

1.8 ± 8.9

0.427

0.198

General health domain

76.8 ± 14.3

79.7 ± 19.1

2.9 ± 16.1

0.463

0.183

  1. * Effect size, the paired Cohen’s d effect size; data, mean ± SD.
  2. SF-36, the 36-Item Short Form Survey, MHC-SF, Mental Health Continuum Short Form, CES-D, Center for Epidemiologic Studies Depression Scale, GAD-7, General Anxiety Disorder-7.
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