Fig. 4
From: Streptozotocin-induced hyperglycemia unmasks cardiotoxicity induced by doxorubicin
Streptozotocin-induced hyperglycemia aggravates cardiac fibrosis in doxorubicin treated mice. (A) Distribution of fibrillar collagens in the left ventricle of a mouse examined by polarized light microscopy after Sirius Red staining. (B) Semi-quantitative analysis of cardiac fibrosis. (C,D) protein expression of Galectin 3 and CD68, respectively, in the cardiac tissue. *p < 0.05, **p < 0.01 and ***p < 0.001 compared to the “Ctl” condition. Scale, 100 µm.
