Table 2 The top five significantly (p-value < 0.03) enriched GO terms and KEGG pathways with cGBs by genecodis 4.
Biological Process | |||
|---|---|---|---|
GO ID | Description | Adj. p-value | Annotated cGBs |
GO:0030330 | DNA Damage Response | 4.70E-05 | MUC1, E2F7 |
GO:2,000,045 | Regulation of G1/S Transition of Mitotic Cell Cycle | 4.12E-04 | RRM2, E2F7 |
GO:0090068 | Positive Regulation of Cell Cycle Process | 5.10E-04 | MUC1, BIRC5, E2F7 |
GO:0042981 | Regulation of Apoptotic Process | 8.05E-04 | TOP2A, ALB, BIRC5 |
GO:1,903,490 | Positive Regulation of Mitotic Cytokinesis | 0.001499 | BIRC5 |
Molecular Function | |||
GO ID | GO function | Adj. p-value | Associated cGBs |
GO:0008301 | DNA Binding, Bending | 0.00509 | TOP2A |
GO:0030170 | Pyridoxal Phosphate Binding | 0.00598 | ALB |
GO:0008170 | N-methyltransferase Activity | 0.00807 | MUC1 |
GO:0005080 | Protein Kinase C Binding | 0.01075 | TOP2A |
GO:0005507 | Copper Ion Binding | 0.01342 | ALB |
KEGG Pathways | |||
KEGG ID | KEGG function | Adj. p-value | Associated cGBs |
hsa00240 | Pyrimidine metabolism | 0.01668 | RRM2, ALB, BIRC5 |
hsa00480 | Glutathione metabolism | 0.01698 | RRM2, MUC1 |
hsa04115 | p53 signaling pathway | 0.02170 | RRM2, TOP2A |
hsa00983 | Drug metabolism | 0.03196 | RRM2 |
hsa05200 | Pathways in cancer | 0.03808 | BIRC5 |
