Table 1 Incidence of Rheumatoid Arthritis in 20–54 aged 20–54 years between 1990 and 2021 at the global and regional level.
Location | Rate per 100 000 (95% UI) | |||||
|---|---|---|---|---|---|---|
1990 | 2021 | 1990–2021 | ||||
Incident cases | Incident rate | Incident cases | Incident rate | Cases change | EAPC | |
Global | 280,445 (230,796 to 335,292) | 11.66 (9.60 to 13.94) | 508,185 (417,807 to 605,687) | 13.48 (11.08 to 16.06) | 0.81 (0.74 to 0.89) | 0.55 (0.52 to 0.57) |
Socio-demographic index | ||||||
High SDI | 76,181 (90,706 to 62,336) | 17.25 (20.53 to 14.11) | 101,854 (121,383 to 84,583) | 19.73 (23.51 to 16.38) | 0.34 (0.3 to 0.37) | 0.51 (0.41 to 0.62) |
High-middle SDI | 65,130 (77,868 to 52,985) | 12.5 (14.95 to 10.17) | 104,743 (124,954 to 85,647) | 16.02 (19.11 to 13.1) | 0.61 (0.5 to 0.73) | 0.85 (0.83 to 0.86) |
Middle SDI | 93,136 (111,447 to 75,641) | 11.87 (14.2 to 9.64) | 180,000 (215,051 to 147,793) | 14.64 (17.49 to 12.02) | 0.93 (0.8 to 1.07) | 0.75 (0.73 to 0.78) |
Low-middle SDI | 35,422 (43,041 to 28,884) | 7.54 (9.17 to 6.15) | 91,651 (111,169 to 75,658) | 10.01 (12.14 to 8.26) | 1.59 (1.5 to 1.67) | 1.06 (0.95 to 1.17) |
Low SDI | 10,349 (12,647 to 8280) | 5.61 (6.86 to 4.49) | 29,612 (35,678 to 23,877) | 6.56 (7.91 to 5.29) | 1.86 (1.8 to 1.93) | 0.61 (0.48 to 0.74) |
Regions | ||||||
Andean Latin America | 2869 (2374 to 3378) | 18.3 (15.14 to 21.54) | 9774 (8154 to 11,440) | 30.02 (25.05 to 35.14) | 2.41 (2.11 to 2.68) | 1.75 (1.67 to 1.84) |
Australasia | 1894 (1464 to 2342) | 18.82 (14.54 to 23.27) | 3353 (2591 to 4112) | 22.99 (17.76 to 28.2) | 0.77 (0.6 to 0.94) | 0.69 (0.45 to 0.93) |
Caribbean | 1262 (1021 to 1503) | 7.94 (6.43 to 9.46) | 2342 (1935 to 2789) | 10.21 (8.44 to 12.16) | 0.86 (0.73 to 1) | 0.81 (0.7 to 0.92) |
Central Asia | 3056 (2519 to 3643) | 10.28 (8.47 to 12.25) | 7155 (6062 to 8219) | 15.34 (13.0 to 17.62) | 1.34 (1.16 to 1.57) | 1.31 (1.21 to 1.41) |
Central Europe | 8494 (6909 to 10,036) | 14.32 (11.65 to 16.92) | 9759 (7887 to 11,627) | 17.85 (14.42 to 21.26) | 0.15 (0.09 to 0.21) | 0.71 (0.67 to 0.75) |
Central Latin America | 14,537 (11,975 to 17,030) | 21.31 (17.56 to 24.97) | 36,667 (31,125 to 42,129) | 29.34 (24.91 to 33.72) | 1.52 (1.4 to 1.65) | 0.95 (0.82 to 1.08) |
Central Sub-Saharan Africa | 1248 (1018 to 1494) | 6.17 (5.03 to 7.39) | 4153 (3395 to 4907) | 7.64 (6.25 to 9.03) | 2.33 (2.16 to 2.48) | 0.76 (0.66 to 0.85) |
East Asia | 86,095 (68,850 to 104,695) | 14.15 (11.32 to 17.21) | 132,281 (106,413 to 161,093) | 17.98 (14.46 to 21.9) | 0.54 (0.4 to 0.7) | 0.88 (0.84 to 0.91) |
Eastern Europe | 13,566 (11,269 to 15,846) | 12.3 (10.21 to 14.36) | 15,156 (12,663 to 17,714) | 15.38 (12.85 to 17.98) | 0.12 (0.05 to 0.17) | 0.63 (0.56 to 0.69) |
Eastern Sub-Saharan Africa | 3541 (2845 to 4276) | 5.22 (4.2 to 6.31) | 10,056 (8091 to 12,085) | 5.86 (4.72 to 7.05) | 1.84 (1.78 to 1.91) | 0.41 (0.32 to 0.5) |
High-income Asia Pacific | 17,988 (14,020 to 22,243) | 20.42 (15.92 to 25.25) | 17,766 (13,745 to 22,025) | 21.11 (16.33 to 26.17) | -0.01 (-0.06 to 0.03) | 0.27 (0.17 to 0.38) |
High-income North America | 22,255 (18,848 to 25,773) | 15.7 (13.3 to 18.18) | 35,155 (29,934 to 40,645) | 20.92 (17.81 to 24.18) | 0.58 (0.52 to 0.65) | 1.04 (0.88 to 1.21) |
North Africa and Middle East | 7447 (6092 to 8883) | 5.55 (4.54 to 6.62) | 25,370 (20,601 to 29,664) | 8.18 (6.64 to 9.56) | 2.41 (2.18 to 2.65) | 1.33 (1.27 to 1.4) |
Oceania | 80 (62 to 101) | 2.96 (2.28 to 3.75) | 221 (173 to 275) | 3.5 (2.75 to 4.36) | 1.77 (1.59 to 1.96) | 0.47 (0.42 to 0.53) |
South Asia | 38,710 (31,077 to 47,778) | 8.49 (6.81 to 10.48) | 105,514 (84,598 to 131,418) | 11.53 (9.25 to 14.37) | 1.73 (1.64 to 1.82) | 1.15 (0.99 to 1.32) |
Southeast Asia | 7559 (5846 to 9395) | 3.72 (2.88 to 4.62) | 18,231 (13,967 to 22,595) | 5.14 (3.94 to 6.37) | 1.41 (1.2 to 1.63) | 1.17 (1.14 to 1.21) |
Southern Latin America | 2666 (2148 to 3169) | 11.99 (9.66 to 14.25) | 6714 (5632 to 7802) | 20.06 (16.83 to 23.31) | 1.52 (1.33 to 1.76) | 1.6 (1.49 to 1.71) |
Southern Sub-Saharan Africa | 5166 (4349 to 6110) | 23.99 (20.2 to 28.38) | 8125 (6796 to 9630) | 20.67 (17.29 to 24.5) | 0.57 (0.5 to 0.65) | -0.33 (-0.41 to -0.24) |
Tropical Latin America | 7951 (6301 to 9765) | 11.67 (9.25 to 14.33) | 12,748 (10,316 to 15,109) | 10.93 (8.84 to 12.95) | 0.6 (0.5 to 0.71) | 0.02 (-0.06 to 0.09) |
Western Europe | 31,641 (25,422 to 38,259) | 16.75 (13.45 to 20.25) | 39,571 (32,005 to 48,344) | 20.13 (16.28 to 24.6) | 0.25 (0.21 to 0.3) | 0.67 (0.6 to 0.75) |
Western Sub-Saharan Africa | 2421 (1863 to 3051) | 3.4 (2.62 to 4.28) | 8075 (6235 to 10,019) | 4.27 (3.3 to 5.3) | 2.34 (2.24 to 2.46) | 0.81 (0.67 to 0.95) |
