Fig. 7

The mediating role of glaucoma endophenotypes in the relationship between circulating CD5 and POAG. CD5, T-cell surface glycoprotein CD5; IOP, intraocular pressure; POAG, primary open-angle glaucoma. Total effect, the effect of CD5 on glaucoma; Mediation effect, the indirect effect of CD5 on POAG via endophenotypes.