Table 2 Testing statistics and efficiency of pooled testing in pools of three with the Abbott HIV-1 VL assay for routine viral load monitoring, for actual cut-off used for individual re-testing (≥ 40 copies/ml) and for two hypothetical scenarios using higher cut-offs for individual re-testing (≥ 120 copies/ml and ≥ 200 copies/ml).
Pool result cut-off for re-testing all specimens in pool individually | ≥ 40 copies/mL | ≥ 120 copies/mL | ≥ 200 copies/mL |
|---|---|---|---|
As implemented | Hypothetical scenarios if using higher cut-off for individual re-testing after pooled testing | ||
Summary statistics | |||
Number of pools with results | 4132 | 4132 | 4132 |
Number of pools with HIV-1 detected above cut-off (and each specimen tested individually) | 814 | 541 | 488 |
Number of specimens with test results produced | 12,396 | 12,396 | 12,396 |
Total number of specimens with results reported as HIV-1 detected after individual re-testing of specimens from pools above cut-off (both suppressed and unsuppressed) | 1168 | 821 | 738 |
Number of specimens with results reported as unsuppressed (> 1,000 copies/mL) | 449 | 444 | 437 |
Proportion of specimens with results > 1,000 copies/mL (unsuppressed) | 3.6% | 3.6% | 3.5% |
Number of assays useda | 6797 | 5950 | 5786 |
Efficiency | |||
Number of tests run per person with result (# of tests/# of specimens with results)a | 0.55 | 0.48 | 0.47 |
Estimated additional people with test results (as compared to individual testing)a | 5409 | 6227 | 6386 |
Estimated % of assays saved (as compared to individual testing)a | 45% | 52% | 53% |
