Fig. 8
From: Screening necroptosis genes influencing osteoarthritis development based on machine learning
CASP1 expression levels in the normal control (NC) and OA groups. (a) qRT-PCR showing the expression levels of CASP1 in NC and OA groups (n = 3 per group). The expression of CASP1 is significantly higher in the OA group than that in the NC group (*P < 0.05). (b) Western blot (WB) analysis of CASP1 and GAPDH in NC and OA groups (n = 3 per group). CASP1 protein levels were higher in the OA group compared to that in the NC group. The full-length, unprocessed blot is included in Supplementary Fig. 2. (c) Quantification of WB results. Relative protein expression of CASP1 normalised to GAPDH is significantly increased in the OA group compared to that in the NC group (P < 0.01).
