Table 3 Serum parameters.

From: Comparison of mechanical resuscitation by an LV Impella device to extracorporeal resuscitation using VAECMO in a large animal model

 

BL

Impella = 8 ECMO = 6

PR 10

Impella = 6 ECMO = 6

PR 30

Impella = 6 ECMO = 6

PR 60

Impella = 6 ECMO = 6

PR 360

Impella = 6 ECMO = 6

AST [U/L]

 Impella

28 ± 8

85 ± 24*

73 ± 10

77 ± 10

52 ± 32

 ECMO

22 ± 9

40 ± 16*

50 ± 23

51 ± 23

38 ± 8

ALT [U/L]

 Impella

51 ± 15

97 ± 54

84 ± 41

74 ± 36

48 ± 10

 ECMO

54 ± 7

54 ± 4

54 ± 4

55 ± 5

54 ± 9

Crea [µmol/L]

 Impella

145 ± 21

176 ± 27

185 ± 32

194 ± 39

171 ± 25

 ECMO

123 ± 15

141 ± 13

143 ± 19

145 ± 25

159 ± 25

Albumin [g/L]

 Impella

31 ± 2

29 ± 2*

28 ± 2***

28 ± 2**

27 ± 2*

 ECMO

25 ± 5

22 ± 4*

21 ± 2***

20 ± 3**

20 ± 5*

CK [U/L]

 Impella

574 ± 216

1337 ± 670

1249 ± 510

1497 ± 673

5241 ± 3971

 ECMO

950 ± 671

1152 ± 474

1164 ± 580

1274 ± 829

3517 ± 1615

CK-MB [U/L]

 Impella

402 ± 348

1143 ± 753

1005 ± 539

1182 ± 433

3811 ± 2370

 ECMO

745 ± 469

1186 ± 787

938 ± 422

985 ± 504

2402 ± 999

S100B [ng/mL]

 Impella

5.9 ± 2

6 ± 1.8

 

14.8 ± 8.8

6.2 ± 2.3

 ECMO

5.8 ± 1.2

10.2 ± 3.7

 

13.9 ± 3.8

6.4 ± 2.4

Myo [ng/mL]

 Impella

332 ± 76

323 ± 55

 

272 ± 57

263 ± 77

 ECMO

379 ± 63

339 ± 127

 

361 ± 95

369 ± 106

PLT [nl−1]

 Impella

280 ± 65

   

334 ± 163

 ECMO

204 ± 37

   

244 ± 88

  1. Blood parameters of 14 swine that were resuscitated with either the Impella ECP or veno-arterial ECMO at baseline (BL), 10 (PR 10), 30 (PR 30), 60 (PR 60) and 360 (PR 360) minutes following the return of spontaneous circulation.
  2. ALT alanine transaminase, AST aspartate transaminase, Crea creatinine, CK creatine kinase, CK-MB creatine kinase-MB, PLT platelet count, S100B S100 calcium binding protein B. Data are presented as the means ± standard deviations.
  3. p > 0.05 if not indicated otherwise, *p < 0.05, **p < 0.01, ***p < 0.001.
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