Table 1 Clinical characteristics of the patients

From: Accelerators of chronic hepatitis B fibrosis cirrhosis CCND1 gene expression and promoter hypomethylation

Variables

HCs (n = 16)

CHB (n = 53)

LCs (n = 71)

Female, n (%)

10 (62)

12 (23)

18 (25)

Male, n (%)

6 (38)

41 (77)

53 (75)

Age (years)

33 (24.75,36)

42 (34,54)

51 (43,54.5)

FIB-4

0.62 (0.44,0.76)

1.16 (0.78,1.59)

2.29 (1.50,3.70)

APRI

0.16 (0.16,0.19)

0.31 (0.25,0.41)

0.59 (0.44,0.95)

LSM

NA

7.7 (6.90,8.30)

15 (12.60,19.05)

PLT ((10^9 /L))

254.5 (237.25,277.75)

199 (166,231)

119 (80,148.50)

AST (U/L)

18.5 (15,20.25)

24 (21,27)

27 (24,34.50)

ALT (U/L)

17.5 (8,22.25)

24 (16,44)

26 (23,33.50)

TBIL (umol/L)

10.1 (6.82,12.40)

12.8 (8.90,17.80)

13.6 (9.80,17.40)

ALB (g/L)

48.8 (47.77,50.17)

47.6 (45.70,49.80)

46.8 (43.50,49.25)

AFP

NA

2.35 (1.71,3.31)

2.54 (1.89,3.78)

HBeAG (IU/ml)

NA

0.65 (0.53,2.13)

0.68 (0.41,1.93)

HBSAG (IU/ml)

NA

2006.08 (810.12,4304.03)

1048.04 (389.50,1894.02)

PTA (%)

109 (99,114)

107 (100,114)

88 (79,99)

INR

0.94 (0.92,0.98)

0.97 (0.93,1)

1.08 (1,1.15)

  1. LC = liver cirrhosis, CHB = chronic hepatitis B, HC = healthy control, ALT = alanine aminotransferase, AST = aspartate aminotransferase, TBIL = total bilirubin, ALB = albumin, INR = international normalized ratio, PTA = prothrombin time activity, AFP = alpha fetoprotein, HBsAg = hepatitis B surface antigen, HBeAG = Hepatitis Be Antigen, FIB-4 = fibrosis-4 score, APRI = aspartate aminotransferase-to-platelet ratio index, NA = not available, LSM = Liver hardness