Table 3 The Cochran’s Q test of Mendelian randomization analyses for BMD and postural instability.
From: A causal association between osteoporosis and postural instability: a Mendelian randomization study
Exposure | Outcome | SNPs selection | method | Cochran’s Q test | ||
|---|---|---|---|---|---|---|
Q | Q_df | Q_pval | ||||
Postural instability | FN-BMD | Complete | IVW | 45.283 | 46 | 0.465 |
MR Egger | 45.162 | 45 | 0.502 | |||
Steiger filtering | IVW | 30.673 | 41 | 0.880 | ||
MR Egger | 20.894 | 40 | 0.878 | |||
LS-BMD | Complete | IVW | 54.597 | 46 | 0.180 | |
MR Egger | 53.897 | 45 | 0.170 | |||
Steiger filtering | IVW | 34.947 | 44 | 0.833 | ||
MR Egger | 34.872 | 43 | 0.806 | |||
FA-BMD | Complete | IVW | 53.178 | 49 | 0.316 | |
MR Egger | 51.296 | 48 | 0.345 | |||
Steiger filtering | IVW | 43.623 | 46 | 0.572 | ||
MR Egger | 43.589 | 45 | 0.531 | |||
