Table 3 Adjusted HRs and 95% CIs for risk of specific-site cancer across the trajectories of life’s essential 8 scores in Kailuan study.

From: The association of life’s essential 8 scores trajectory patterns with the risk of all cancer types

 

LE8 scores trajectory patterns

P for trend

Low-stable

Moderate-stable

Elevated-stable

Head and neck cancer

Ref.

0.81 (0.58,1.13)

0.77 (0.51, 1.14)

0.366

Lung cancer

Ref.

0.86 (0.71, 1.04)

0.73 (0.57,0.92)

0.033

Breast cancera

Ref.

0.51 (0.35, 0.77)

0.49 (0.32, 0.77)

0.002

Kidney cancer

Ref.

1.30 (0.79, 2.13)

0.81 (0.43, 1.54)

0.171

Bladder cancer

Ref.

1.51 (0.83, 2.75)

1.20 (0.59, 2.42)

0.328

Prostatic cancera

Ref.

0.68 (0.39, 1.21)

0.80 (0.41, 1.58)

0.419

Esophageal cancer

Ref.

1.09 (0.62, 1.92)

1.26 (0.65, 2.44)

0.789

Stomach cancer

Ref.

0.77 (0.53, 1.12)

0.83 (0.53, 1.30)

0.391

Colorectal cancer

Ref.

0.81 (0.62, 1.06)

0.69 (0.50, 0.97)

0.093

Pancreatic cancer

Ref.

0.92 (0.46, 1.84)

0.99 (0.44, 2.23)

0.960

Liver cancerb

Ref.

0.66 (0.46, 0.95)

0.61 (0.39, 0.95)

0.042

Gallbladder and extrahepatic bile duct cancerc

Ref.

2.27 (0.65, 7.92)

1.67 (0.38, 7.31)

0.413

Leukemia and lymphoma

Ref.

0.90 (0.51, 1.59)

0.76 (0.36, 1.57)

0.754

Endometrial and cervical cancera

Ref.

0.63 (0.29, 1.34)

0.62 (0.27, 1.43)

0.452

  1. Adjusted models include age, gender, WC, CRP, drinking status, marital status, family income, and sedentary lifestyles.
  2. Results presented with bold valued were statistically significant with all p value < 0.05.
  3. a: Conducted only in men or women.
  4. b: Further adjusted for HBV infection, liver cirrhosis and fatty liver disease.
  5. c: Further adjusted for gallstone disease and gallbladder polyp.