Table 2 Combination index.

From: Nanoemulsification of PTX and BEZ235 inhibits colon cancer growth

Cell

Concentration(nM)

Cell survival rate (%)

*CI

BEZ235

PTX

BEZ235

PTX

NEs-1:10

HT29

25

1

0.9

0.83

0.66

0.88

HCT116

25

1

0.9

0.81

0.58

0.80

 

NE-BE235

NE-PTX

NE-BE235

NE-PTX

NEs-1:10

 

HT29-DDP

50

10

0.89

0.65

0.45

0.78

HCT116-LOHP

50

10

0.85

0.6

0.46

0.90

  1. *CI = \(\frac{\text{availability of NEs}-1:10}{\text{Cell availabity of NE}-\text{PTX}\times \text{ cell availability of BEZ}235}\)
  2. CI < 1, = 1 and > 1 indicated synergic, additive and antagonistic effect, respectively.
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