Fig. 5 | Scientific Reports

Fig. 5

From: Conserved marseilleviruses harboring diverse antibiotic resistance genes isolated from the Yangtze river Delta and the Pearl river delta, China

Fig. 5

Primary and secondary structure of bacterial and viral SMRs. (A) Multiple amino acid sequence alignments of bacterial and viral SMRs using MAFFT alignment. High consensus residues are highlighted in red. Secondary structures of TM helices are represented above and below the multiple sequence alignments, respectively. RCSB accession numbers for E. coli SMRs: 7MH6.A and 2I68.A. NCBI accession numbers for viral SMRs: Shanghaivirus strain J2016JW (MarSH128, AVR52833.1), Dashavirus strain R2023E (MarDSR188, WNL50227.1), Tunisfontainevirus strain 484 (TNSORF421, AHC55139.1), Brazilianmarseillevirus strain BH2014 (ORFR113, YP_009238618.1), and Goldenmarseillevirus strain Golden (GMAR39, YP_009310156.1). (B) Secondary structures of Dashavirus SMR (MarDSR188, left) and E. coli SMR (2I68.A, right). Highly conserved residues between different species are in violet circles and conserved residues within marseilleviruses are in medium turquoise circles. Residues of E. coli SMR reported to be implicated in substrate binding and transport13 are highlighted with red frame. The four TM helices are indicated in bold and the membrane shown by the light orange box.

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