Fig. 1
From: Neurodegenerative and neuroinflammatory changes in SOD1-ALS patients receiving tofersen

(A–D): Trend of NfL (A), NfH (B), SerpinA1 (C), and CHI3L1 (D) in CSF, after logarithmic transformation to normalize data, since the first Tofersen injection. CHI3L1, chitinase 3 like-1; CSF, cerebrospinal fluid; NfH, neurofilament heavy chain; NfL, neurofilament light chain.